Human cells

Human Cells: Scientists do not even know half the information inside the human cells

Health Health science

Human cells are a world in themselves. It contains millions of proteins involved in many very active processes that sustain the lives of us humans and enable us to remain active. To study all the diseases and disorders of the human body properly, it is very important to know all these proteins. Scientists have developed a technique that will use artificial intelligence to collect data from microscopic images of cells and create a unified map of their components, more than half of which is yet to be seen.

Map work will now be possible
Researchers will now use artificial intelligence to collect data from microscopy images and biochemically analyze them to create a unified map of the cell’s components. Terry Eiker, a network biologist and computer scientist at the University of California, San Diego, said scientists knew that Zam didn’t know much more than he knew for a long time.

Act on the components of cells
Iker said that now we have found a way through which we can know a lot more. Cells are very fine, and they and their components can only be seen through a powerful microscope. It also contains the energy-providing mitochondria and the protein-making factory ribosomes. Now, these proteins can be identified and monitored by adding dye to the cells.

There may be finer work
Biochemistry techniques can go even further and perform many finer tasks, such as binding a targeted antibody to a protein, removing it from cells, or ensuring that it is attached. Combining these methods was a challenging task for cell biologists.

AI can make it possible
Eicher explained that a long-standing obstacle in the life sciences was how to overcome the difference between the micron and nanometer scales. It can now be done through artificial intelligence by studying data from multiple sources and integrating them into models of cells from systems.

Photos from around the world?
Eyker and his colleagues observed the components in maps of cells in books from around the world and tried to learn the interactions of proteins and their distances. He built a machine-learning algorithm from the available maps and images from the Human Protein Atlas Library.

Shocking discovery
Through this algorithm, they wanted to find the distance between the pairs of proteins. Their goal was to find communities of proteins, called assemblies, that exist in the cell at different scales ranging from 50 nanometers to one micrometre. The algorithm determined a set of 70 protein communities. In this study, published in Nature, the researchers also found that more than half of the newly identified protein components were previously unknown to science.

Even before this, scientists have made efforts to make an internal map of human cells. In this research, researchers have also developed such a technique so that the interactions and activities of proteins inside cells can be observed and monitored. It is expected that this will help in finding treatment for many diseases in future.